Resistance Training to Individuals for Cognitive Impairment With Dementia

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorUniversity of Beira Interior

About this trial

This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.

Eligibility criteria

Qualifiers

Clinical diagnosis of mild cognitive impairment

SPPB score ≥ 3 points

Willingness to participate in the interventions and collaborate with the research team

Must be able to provide informed consent (oral or written)

Disqualifiers

Severe dementia

Severe comorbidity that negatively influences participation in the intervention

Color blindness

Fractures in the last three months

Trial design

Treatments tested in this trial

  • One Resistance Training Set (Single Session)
  • Three Resistance Training Sets (Single Session)
  • One Resistance Training Set (8 Weeks)
  • Three Resistance Training Sets (8 Weeks)
  • Control (8 Weeks)

Treatment groups

80 Participants
are divided into 5 treatment groups

Sponsors and collaborators

University of Beira Interior

Lead sponsor

Research Center in Sports Sciences, Health Sciences and Human Development

Collaborator