About this trial
This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.
Eligibility criteria
Qualifiers
Clinical diagnosis of mild cognitive impairment
SPPB score ≥ 3 points
Willingness to participate in the interventions and collaborate with the research team
Must be able to provide informed consent (oral or written)
Disqualifiers
Severe dementia
Severe comorbidity that negatively influences participation in the intervention
Color blindness
Fractures in the last three months
Trial design
Treatments tested in this trial
- One Resistance Training Set (Single Session)
- Three Resistance Training Sets (Single Session)
- One Resistance Training Set (8 Weeks)
- Three Resistance Training Sets (8 Weeks)
- Control (8 Weeks)
Treatment groups
Sponsors and collaborators
University of Beira Interior
Lead sponsor
Research Center in Sports Sciences, Health Sciences and Human Development
Collaborator