Respiratory Functions, Thoracoabdominal Movements and Exercise Capacity in Neuromuscular Diseases

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age5-15
SponsorLokman Hekim University

About this trial

The clinical trial titled "Investigation of Respiratory Functions, Thoracoabdominal Movements, and Exercise Capacity in Neuromuscular Diseases" aims to evaluate the respiratory functions, thoracoabdominal movements, and exercise capacity in children with Duchenne Muscular Dystrophy (DMD) and Spinal Muscular Atrophy (SMA) compared to healthy controls. The study will use spirometry, structured light plethysmography (SLP), the six-minute walk test, and the six-minute pegboard ring test to assess these functions. This trial will be conducted at the Lokman Hekim University Muscle and Nerve Diseases Application and Research Center from May 2024 to Dec 2025.

Eligibility criteria

Qualifiers

Duchenne Muscular Dystrophy (DMD)

Clinically diagnosed with Duchenne Muscular Dystrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study.

Disqualifiers

Spinal Muscular Atrophy (SMA)

Healthy Controls

Trial design

Treatments tested in this trial

  • Respiratory Function Test
  • Structured light plethysmography
  • 6 Minute Walking Test
  • 6-Minute Peg Board Ring Test
  • Hand Grip Strength

Treatment groups

42 Participants
are divided into 3 treatment groups

Sponsors and collaborators