About this trial
The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are:
* Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information? * Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information? * Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information?
Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.
Eligibility criteria
Qualifiers
Parkinson's Disease diagnostic
Stage 1 or 2 Hoenh-Yahr scale
Taking immediate-release Levodopa
MoCA score of 26 or above
Disqualifiers
Dementia
Other neurodegenerative disease
History of substance abuse
History of hearing disorders
Trial design
Treatments tested in this trial
- Withholding Levodopa