To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
Histologically confirmed gastroesophageal adenocarcinoma;
R0 resectable Siewert Ⅱ, cT2-3N0-3M0 (AJCC V8 TNM classification);
Have a performance status of 0 or 1 on the ECOG Performance Scale;
Age 18-80 years old, both men and women;
Have a history of other malignant tumors in the past or at the same time;
Previous upper abdominal surgery (excluding cholecystectomy);
Bleeding, perforation and obstruction requiring emergency surgical treatment;
Severe heart, lung, liver and kidney dysfunction, which the researcher thinks is not suitable for operation;