Risk-Stratified Hypofractionated Radiotherapy After Breast-Conserving Surgery for Early Breast Cancer

ConditionsEarly Stage Breast Carcinoma Breast Cancer

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexFemale

Age18-75

SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

This prospective study is designed to evaluate the feasibility, efficacy, and safety of risk-stratified hypofractionated radiotherapy after breast-conserving surgery in patients with early breast cancer.

Eligibility criteria

Qualifiers

ECOG performance status score of 0 to 2.

Pathologically confirmed breast cancer, including invasive carcinoma or ductal carcinoma in situ.

Clinical stage cT0-2N0M0.

Underwent breast-conserving surgery.

Disqualifiers

Regional lymph node metastasis.

Distant metastasis.

Bilateral breast cancer.

Prior thoracic radiotherapy.

Trial design

Treatments tested in this trial

Whole-breast irradiation and tumor bed boost
Partial-breast irradiation

Treatment groups

649 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Lead sponsor

Source ClinicalTrials.gov