PANACOTTA is a multicenter randomized controlled trial including patients with symptomatic chronic pancreatitis and a dilated main pancreatic duct to either robot-assisted or open lateral pancreaticojejunostomy. The PANACOTTA trial will assess the post-operative quality of recovery following robot-assisted versus open lateral pancreaticojejunostomy.
At least 18 years old
Indication for (extended or partial) lateral pancreaticojejunostomy as agreed during multidisciplinary team meeting based on symptomatic chronic pancreatitis (i.e. morphine dependent pain or recurrent acute flares of pancreatitis, at least 3 episodes per year) and a dilated pancreatic duct of ≥ 5 mm, with a non-enlarged pancreatic head < 40 mm
Confirmed CP, according to the M-ANNHEIM diagnostic Criteria24
Eligible for both an robot-assisted and open approach
Suspected or confirmed current pancreatic cancer
ASA classification ≥ 4
Other painful conditions aside from CP, with pain difficult to discriminate from CP pain
Prior pancreatic surgery
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lead sponsor
St. Antonius Hospital
Collaborator
Erasmus Medical Center
Collaborator
Maastricht University Medical Center
Collaborator
Universitätsklinikum Hamburg-Eppendorf
Collaborator
University Medical Center Groningen
Collaborator
Onze Lieve Vrouwe Gasthuis
Collaborator
Catharina Ziekenhuis Eindhoven
Collaborator
Radboud University Medical Center
Collaborator
Medisch Spectrum Twente
Collaborator
Leiden University Medical Center
Collaborator