Role of Acetaldehyde in the Development of Oral Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorMasonic Cancer Center, University of Minnesota
About this trial
This is a minimal risk intervention study where healthy volunteers and individuals with Fanconi anemia will consume a single dose of alcohol and provide primarily non-invasive biological samples at various time points. Biospecimens to be collected include saliva, oral cells collected via mouthwash and cheek brush, and urine. The collection of two blood samples (5 mL each) will be optional and banked for future use.
Eligibility criteria
Qualifiers
21-45 years of age for alcohol drinkers
Occasionally consume alcohol
At least 1 drink per month for healthy volunteers
At least 1 drink in the last 3 months for Fanconi anemia patients
Disqualifiers
Pregnant or nursing
Taking any medication or drug that might affect alcohol use and absorption or that might be affected by alcohol consumption
Healthy volunteers who have taken any antibiotics in the last 3 months
Currently consuming more than 21 drinks per week
Trial design
Treatments tested in this trial
- Alcohol
- Biospecimen Collection
- Breath Test
Treatment groups
170 Participants
are divided into 2 treatment groupsSponsors and collaborators
Masonic Cancer Center, University of Minnesota
Lead sponsor
National Institutes of Health (NIH)
Collaborator
Source ClinicalTrials.gov