Role of Corneal Nerves in Dry Eye Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorDaniela Nosch

About this trial

This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to investigate whether these factors vary based on the severity of dry eye symptoms.

Eligibility criteria

Qualifiers

Group with DED: Diagnosis of DED based on the TFOS DEWS II report

Group without DED: No diagnosis of DED

Disqualifiers

Systemic disease that may affect ocular health and innervation

injury or history of operations on the anterior or posterior segment of the eye, which can affect the corneal structure and physiology

regular application of systemic or ocular medication known to affect the tear film except from DED medications

eye drops or makeup on the day of measurement.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

140 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Daniela Nosch

Lead sponsor

University of Applied Sciences and Arts Northwestern Switzerland

Sponsor institution