Role of Sleep Reactivity in Shift Work Disorder
ConditionShift-work Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHenry Ford Health System
About this trial
The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.
Eligibility criteria
Qualifiers
Participants must be working a fixed nightshift schedule, operationalized as: a) working at least three night shifts a week, b) shifts must begin between 18:00 and 02:00, and last between 8 to 12 hours, and c) must also plan to maintain the nightshift schedule for the duration of the study
Participants must have Shift Work Disorder, which will be diagnosed based on ICSD-3 criteria
Participants must show circadian misalignment, operationalized as a baseline melatonin onset between 18:00 and 01:00.
Participants must be at least 18 years old
Disqualifiers
Insomnia disorder or excessive sleepiness predating the onset of shift work
Termination of nightshift schedule
Presence of other sleep disorders (e.g. obstructive sleep apnea, narcolepsy) determined by standard clinical polysomnography
Diagnosis of bipolar disorder
Trial design
Treatments tested in this trial
- Active phototherapy
- Control phototherapy
- Cognitive Behavioral Therapy (CBT)
- Sleep education control
Treatment groups
150 Participants
are divided into 4 treatment groupsSponsors and collaborators
Henry Ford Health System
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov