About this trial
Cryptorchidism is the most frequent congenital defect of the male newborn. It requires surgery in childhood, increases the risk of fertility disorders and cancer. As a major public health objective, it's the subject of numerous recommendations. Its frequency is increasing in some countries faster than a single genetic cause could not explain it. It may occurs in a geographic cluster. The cause of cryptorchidism involves genetic, hormonal and environmental factors. Animal studies suggest that endocrine disruptors interfere with fetal testicular migration. The aim of the study is to find out if some environmental exposition may be associated with cryptorchidism.
Eligibility criteria
Qualifiers
None
Disqualifiers
Parents of children without endocrine disease. (adrenal, hypothalamic-pituitary, phosphocalcic, thyroid, diabetes, etc.)
Parents of children without an associated genital or urinary defect (hypospadias, micropenis, renal and bladder abnormalities)
Testicular Ectopia (testis outside of normal migration path)
Anorchidism and evanescent testicles, united or bilateral
Trial design
Treatments tested in this trial
- Measure of the exposure of parent of male with /without cryptorchidism to endocrine disruptors
Treatment groups
Sponsors and collaborators
University Hospital, Montpellier
Lead sponsor
University Hospital, Bordeaux
Collaborator