Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis
ConditionAutoimmune Hepatitis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-18
SponsorAssiut University
1. To evaluate the immunohistochemical expression of USP35 in cases of juvenile autoimmune hepatitis and control cases. 2. To correlate this with the level of necro-inflammation and extent of fibrosis using Massion's trichrome stain in cases of juvenile autoimmune hepatitis.
Patients aged between one day and 18 years (children)
patients diagnosed clinically and physically with juvenile autoimmune hepatitis including seronegative autoimmune hepatitis cases
Cases with inadequate tissue in the paraffin block
Children with viral hepatitis
patients above the age of 18 years old