The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases (obesity, pre-diabetes and type-2 diabetes, dyslipidemia, non-alcoholic fatty liver disease, cardiovascular disease, etc.), nutrition, and metabolism (the process by which a substance is handled in your body) at the University of Missouri. As technology changes and we start to use new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure we are getting accurate results. Reproducibility means performing the same test more than once to see if the same results can be achieved each time.
≥18 and ≤75 years of age
body mass index ≥18.5 and ≤45 kg/m2
Weight stable (i.e., ≤3% change)
≤150 min of structured exercise/week for at least 2 months before entering the study
<18 and >75 years of age
body mass index <18.5 or >45 kg/m2
history of or current significant organ system dysfunction (e.g., heart disease, stroke, diabetes, cancer in remission for <5 years, dementia, chronic kidney disease)
allergies or intolerances to meal ingredients, vegans or vegetarians
Bettina Mittendorfer
Lead sponsor
University of Missouri-Columbia
Sponsor institution