Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorMassachusetts General Hospital

About this trial

After having a baby, some women develop a condition called postpartum depression, or PPD, which can cause sadness, anxiety, and difficulty bonding with their newborn. Right now, most women aren't screened for PPD until about 6 to 8 weeks after giving birth, but this study wants to find out if checking earlier could help identify signs sooner. To test this, researchers will work with 428 women who deliver at an MGH hospital clinic and have no history of depression. Each woman will be randomly placed into one of two groups: one group will fill out a short depression questionnaire online at 2 to 3 weeks after delivery, while the other group will follow the usual process and complete the same questionnaire at their regular 6-week visit. The results will go to each woman's doctor, who will decide if any follow-up care is needed, just like they normally would. The study will follow each participant for 6 months after delivery to see whether earlier screening makes a difference.

Eligibility criteria

Qualifiers

Live birth, term (≥37 weeks) delivery at Massachusetts General Hospital

Access to Patient Gateway, as to receive the electronic EPDS scale

Primary obstetric provider at MGH or its affiliated clinics

No recent history of depressive disorder as determined through diagnoses or medication use*

Disqualifiers

A diagnosis code in the EHR for major depressive disorder, bipolar disorder, or psychotic disorder within the year prior to delivery

Antidepressant, antipsychotic, or bipolar medication use within the year prior to delivery

Age <18 years old

Trial design

Treatments tested in this trial

  • Early PPD Screening

Treatment groups

428 Participants
are divided into 4 treatment groups

Locations

This trial has no locations

Sponsors and collaborators