This is a multicenter, prospective, observational, community-based study designed to evaluate the incidence of respiratory syncytial virus (RSV) infection among community-dwelling elderly individuals in China, as well as their cohabiting older adults and children, over a 24-month period. During the study, home visits will be conducted to collect nasopharyngeal (NP) swabs from all community residents aged ≥50 years who report symptoms of acute respiratory infection (ARI). Pathogen detection will be performed using both point-of-care testing (POCT) and centralized laboratory analysis.
Male or female adults aged ≥50 years (calculated based on date of birth and date of visit).
At least two respiratory symptoms/signs within 48 hours prior to self-reporting OR
At least one respiratory symptom/sign + one systemic symptom/sign within 48 hours prior to self-reporting
Provision of written informed consent by the participant or their legal guardian, in accordance with local EC (Ethics Committee) requirements.
Enrollment in the CRE-ARI group within the preceding 14 days.
Enrollment in the CRE-ARI group has been more than 4 times during the previous 12 months (applicable only to the CRE-ARI group enrollment).
For CAI group, if a household has been enrolled into CAI group within the previous 12 months.
Residence outside the designated study catchment area.
Huashan Hospital
Lead sponsor
Shanghai Huashen Institute of Microbes and Infections
Collaborator