About this trial
This study aims to evaluate whether an innovative combination therapy (CLL1 CAR-T sequential allogeneic hematopoietic stem cell transplantation) is safe, feasible and effective for the treatment of relapsed/refractory acute myeloid leukemia (R/R AML).
Eligibility criteria
Qualifiers
Patients or their guardians understand and voluntarily sign the informed consent form, and are expected to complete the follow-up examinations and treatments as required by the study protocol.
Disqualifiers
History of other malignancies within 3 years prior to screening, except for adequately treated cervical carcinoma in situ, papillary thyroid carcinoma, basal cell or squamous cell skin carcinoma, locally treated prostate cancer after radical treatment, and ductal carcinoma in situ after radical treatment.
Trial design
Treatments tested in this trial
- CLL1 CAR-T Cell Sequential Allogeneic Hematopoietic Stem Cell Transplantation
Treatment groups
Sponsors and collaborators
Donghua Zhang
Lead sponsor
Tongji Hospital
Sponsor institution