Safety and Efficacy of Degradable Magnesium Metal Clips in Surgical Margins of Radical Surgery for Malignant Bone and Soft Tissue Tumors

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorGuangdong Provincial People's Hospital

About this trial

To verify and evaluate the safety and efficacy of biodegradable magnesium metal clips in the surgical margins of radical surgery for bone and soft tissue malignant tumors.

Eligibility criteria

Qualifiers

Participants must be of either gender, aged between 18 and 65 years;

Diagnosis must be confirmed pathologically as osteosarcoma, synovial sarcoma, liposarcoma, or other bone and soft tissue sarcomas;

Must have undergone standard chemotherapy and require en bloc resection;

Participants must voluntarily enroll and sign an informed consent form; willing to closely cooperate with the physician to comply with all study requirements, including participation in all follow-up and assessments.

Disqualifiers

Severe dysfunction of the heart, liver, kidney, lung, or brain.

Pregnant women or women who are breastfeeding.

History of autoimmune disease, HIV infection, history of immunosuppressive disorder, or currently taking immunosuppressive drugs.

History of syphilis (Treponema pallidum), active infection with hepatitis B or C, and positive for verified antigens.

Trial design

Treatments tested in this trial

  • Biodegradable Magnesium Metal Clips

Treatment groups

98 Participants
are divided into 2 treatment groups