About this trial
Patients undergoing particular intensive and (sub)myeloablative chemotherapy regimens with subsequent autologous stem cell transplant currently have a relatively low rate of therapy-related complications, both infectious and non-infectious (organ damage), and can therefore benefit from a specific multidisciplinary care programme at home. In this clinical context, early discharge and domicile of the patient after therapy provided in a hospital setting may represent a procedure designed to better intercept the patient's personal needs. In addition, it may make it possible to increase the limited availability of beds in the face of the progressive increase in demand, allowing the provision of hospital therapies to a higher number of patients with a consequent reduction in pre-hospital waiting times.
Eligibility criteria
Qualifiers
Diagnosis of haematological malignancy undergoing high-dose chemotherapy (sub- or myeloablative)
Age between 18-75 years
WHO Performance Status < 2 or Karnofsky ≥ 60%
FE≥ 50% and absence of significant electrocardiographic changes
Disqualifiers
Diagnosis of haematological malignancy at onset or in progression
Significant cardiovascular disease: heart failure NYHA class 3 or 4, uncontrolled angina, history of myocardial infarction, unstable angina or stroke in the previous 6 months, uncontrolled hypertension, significant arrhythmias not controlled by medication
Trial design
Treatments tested in this trial
- Home patient management
- Hospital patient management