The effects of regular exercise on asthma control has not yet been well demonstrated.
The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.
asthmatic patient
aged 18- 65 years
ACQ > 1.5
stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene
IMC > 35
severe osteoarthritis of the knees and hips
unstable angor
Severe uncontrolled hypertension