SARcopenia and Simplified Geriatric Assessment in Lymphoma Patients Undergoing CAR-T Cell Therapy: the FIL_SAR-CAR Project

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorFondazione Italiana Linfomi - ETS

About this trial

This is a multicenter prospective observational study lead by the FIL on sarcopenia and sGA as possible predictors of efficacy and toxicity outcomes in patients undergoing CAR-T cells treatment.

Eligibility criteria

Qualifiers

Adult patients (≥ 18 years old).

Patients with B-cell non-Hodgkin Lymphoma scheduled to received CAR-T cell product according to Agenzia Italiana del Farmaco (AIFA) indications and technical data sheet of the drug

Availability of a 18F-FDG PET/CT scan or a full dose CT scan (without contrast media) pre-treatment with CART

Written informed consent voluntarily provided

Disqualifiers

Patients not fulfilling the eligibility criteria

Trial design

Treatments tested in this trial

  • Chimeric Antigen Receptor T-cells (CAR-T) therapy

Treatment groups

130 Participants
are divided into 1 treatment group

Sponsors and collaborators

Fondazione Italiana Linfomi - ETS

Lead sponsor

Kite, A Gilead Company

Collaborator