School Inner City Air Study
ConditionViral Infection
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-90
SponsorMassachusetts General Hospital
About this trial
The goal of this randomized clinical trial is to test the efficacy of high efficiency particulate air (HEPA) cleaners in reducing respiratory viral exposure and infections in elementary school classrooms. Classrooms will be randomized to active vs. sham HEPA cleaners. The main questions it aims to answer are:
* Do classroom HEPA cleaners reduce exposure to viruses? * Do classroom HEPA cleaners reduce student and teacher infections? * Do classroom HEPA cleaners reduce infections in family members?
Eligibility criteria
Qualifiers
Grades K-5 (age 6-12 years)
Attend one of the schools that the study team has permission to obtain classroom/school environmental samples
Have no plans to move schools within the upcoming 12 months
Subject and/or parent guardian must be able to understand and provide informed consent and also willing to participate in the study
Disqualifiers
Contraindication to or inability to participate in home self-collection of nasal swab samples
Severe chronic diseases (e.g. cancer, genetic or congenital disorders interfering with mobility)
Severe neurobehavioral, neurodevelopmental or psychiatric disorders requiring special assistance
Families who do not speak English or Spanish well enough to complete the survey questions, as validated versions in other languages are not available for all of the measures
Trial design
Treatments tested in this trial
- Active classroom HEPA cleaner
- Sham classroom HEPA cleaner
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Massachusetts General Hospital
Lead sponsor
Boston Children's Hospital
Collaborator
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator
Source ClinicalTrials.gov