Scrambler Therapy in Chronic Pancreatitis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorJohns Hopkins University

About this trial

The investigators will enroll adults with chronic pancreatitis who have persistent abdominal pain not relieved by standard treatments. This study will test the feasibility and effectiveness of Scrambler Therapy, a non-invasive FDA-cleared device that delivers "non-pain" electrical signals through the skin to retrain the brain's pain perception. Participants will undergo 5-10 treatment sessions and be followed for 3 months with standardized pain scores and quality-of-life assessments. The goal is to generate pilot data to support larger studies of Scrambler Therapy as a novel option for pancreatic pain.

Eligibility criteria

Qualifiers

Adults aged 18 years and older

Diagnosis of chronic pancreatitis with refractory abdominal pain

Able to provide written informed consent in English

Sufficient English language ability to complete study questionnaires

Disqualifiers

Unable or unwilling to provide written consent

History or presence of a significant medical or psychiatric condition that would interfere with study participation

Pregnant or lactating women

Coronary stents or implanted metallic/electrical devices (pacemaker, defibrillator, aneurysm clips)

Trial design

Treatments tested in this trial

  • Scrambler Therapy

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

Johns Hopkins University

Lead sponsor

The National Pancreas Foundation

Collaborator