About this trial
The investigators will enroll adults with chronic pancreatitis who have persistent abdominal pain not relieved by standard treatments. This study will test the feasibility and effectiveness of Scrambler Therapy, a non-invasive FDA-cleared device that delivers "non-pain" electrical signals through the skin to retrain the brain's pain perception. Participants will undergo 5-10 treatment sessions and be followed for 3 months with standardized pain scores and quality-of-life assessments. The goal is to generate pilot data to support larger studies of Scrambler Therapy as a novel option for pancreatic pain.
Eligibility criteria
Qualifiers
Adults aged 18 years and older
Diagnosis of chronic pancreatitis with refractory abdominal pain
Able to provide written informed consent in English
Sufficient English language ability to complete study questionnaires
Disqualifiers
Unable or unwilling to provide written consent
History or presence of a significant medical or psychiatric condition that would interfere with study participation
Pregnant or lactating women
Coronary stents or implanted metallic/electrical devices (pacemaker, defibrillator, aneurysm clips)
Trial design
Treatments tested in this trial
- Scrambler Therapy
Treatment groups
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
The National Pancreas Foundation
Collaborator