Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30-69
SponsorZhongshan People's Hospital, Guangdong, China

About this trial

All participants will be tested for EBV-related biomarkers, including EBNA1-IgA, VCA-IgA, and BNLF2b total antibody (P85-Ab), and participants with high serologic risk will be selected based on serologic test results, and dual-energy CT will be performed first for high-risk screening subjects, and dual-energy CT will be performed first for the high-risk group to record dual-energy CT examinations of those suspected of nasopharyngeal carcinoma, and then endoscopy was performed on the high-risk group to record those suspected of nasopharyngeal carcinoma under endoscopy, and finally biopsies were taken for positive lesion sites indicated by dual-energy CT and suspicious lesion sites found by endoscopy to clarify the diagnosis.

Eligibility criteria

Qualifiers

Subject residents in Zhongshan City

Subject has no medical record of nasopharyngeal carcinoma

Subject is able to comprehend, sign, and date the written informed consent document to participate in the study

Subject has psychical condition and well consciousness, and also accept and cooperate with the follow-up of this study

Disqualifiers

Subject has heavy cardiovascular, liver or kidney disease

Subject has contraindications to nasopharyngeal endoscopy

Subject has contrast media allergy

Trial design

Treatments tested in this trial

  • participants will undergo dual-energy CT and endoscopy

Treatment groups

12,000 Participants
are divided into 1 treatment group