Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorDirection Centrale du Service de Santé des Armées

About this trial

Immersion Pulmonary Edema (IPE) is a relatively new form of hemodynamic pulmonary edema. The number of cases has been increasing over the last ten years and it has become the second most common cause of hospitalization for military divers, after decompression sickness. The pathophysiological mechanisms of IPE are not completely known. Its occurrence is linked to a combination of factors related to the environmental constraints of diving, as well as to the diver's equipment. The main external factors are increased hydrostatic pressure, cold, intense effort and emotional stress. The impact of internal factors is not known. At this time, no severe forms of IPE have been identified in the military. However, it is important to identify this pathology at an early stage, even if the signs appear minor, because the continuation of underwater activity can significantly worsen the clinical picture. The risk of recurrence (greater than 15%) could result in a severe or even lethal accident.

Eligibility criteria

Qualifiers

Military or civilian diver with at least 100 dives

Between the ages of 18 and 60

Good physical condition (able to run/swim for 30 minutes at a constant pace).

Disqualifiers

Divers with a current temporary medical incapacity to dive

Persons with contraindications to physical exercise and/or scuba diving

Pregnant or breastfeeding women

Trial design

Treatments tested in this trial

  • Terrestrial exercise
  • Swimming exercise
  • Transthoracic cardiac ultrasound
  • Transthoracic pulmonary ultrasound
  • Blood collection

Treatment groups

63 Participants
are divided into 2 treatment groups