Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Latvia
About this trial
The study is aimed to determine the potential of volatile marker testing for gastric cancer screening.
The study will be addressing the role of confounding factors, including lifestyle factors, diet, smoking as well as addressing the potential role of microbiota in the composition of exhaled volatile markers.
Eligibility criteria
Qualifiers
Patients with verified gastric cancer (Group 1 & 2)
Patients undergoing or having undergone upper endoscopy according to clinical indications (Group 3 & 5)
Average-risk population group aged 40-64 at inclusion without alarm symptoms (Group 4)
Motivation to participate in the study
Disqualifiers
Known other active cancer
Ventilation problems, airway obstruction
Unwillingness or inability to co-operate
Trial design
Treatments tested in this trial
- Breath sampling for VOC detection
- Surgery material collection for VOC headspace analysis
- Upper endoscopy
- Microbiota testing
Treatment groups
5,000 Participants
are divided into 5 treatment groupsSponsors and collaborators
University of Latvia
Lead sponsor
Technion, Israel Institute of Technology
Collaborator
University of Ulm
Collaborator
Uppsala University
Collaborator
JLM Innovation GmbH
Collaborator
Universitaet Innsbruck
Collaborator
Hospital Universitario San Ignacio
Collaborator
Universidad de Pamplona
Collaborator
Pontificia Universidad Catolica de Chile
Collaborator
AC Camargo Cancer Center
Collaborator
National Cancer Institute of Ukraine
Collaborator
VTT Technical Research Centre of Finland
Collaborator
Source ClinicalTrials.gov