Sebum Metabolomics and Lipidomics for Clinical Applications
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20+
SponsorNational Taiwan University Hospital
About this trial
This study aims to develop a standardized workflow for sebum sampling and metabolomics/lipidomics analysis using Sebutape. A total of 200 participants will be recruited, including healthy individuals, patients with skin diseases, individuals undergoing dermatological treatments or using skincare products, and a subset of healthy participants receiving short-term topical antibiotic intervention. The study will investigate sebum composition, skin microbiome profiles, and their interactions under different conditions to explore potential biomarkers and clinical applications.
Eligibility criteria
Qualifiers
Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be in good health and suitable for participation.
No diagnosed skin diseases or chronic systemic diseases.
No use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
Disqualifiers
Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
Presence of acute or chronic skin diseases, or chronic systemic diseases.
Use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
Trial design
Treatments tested in this trial
- Sebutape sampling
- Bacitracin/Polymyxin B/Neomycin ointment (Yentuogin ointment)
Treatment groups
200 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov