Secretin in Refeeding

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age13-24
SponsorUniversity of California, Los Angeles

About this trial

Patients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secretin--may control both urine output and how the body handles acid and base. This study will evaluate whether secretin levels are different in anorexic patients who urinate an excessive amount compared to those who urinate normal amounts. For this study, patients will have one extra blood draw before and after one meal during their hospitalization. The blood draw before the meal coincides with a standard of care blood draw. Also after the meal, subjects will be asked to provide one extra urine sample. Information from subject's medical records will also be used.

Eligibility criteria

Qualifiers

male and female patients

age 13-24 years

diagnosis of restrictive-type anorexia nervosa

hospitalization for nutritional support

Disqualifiers

5150 hold

Anti-depressant, anti-psychotic, or anticonvulsant medications

Previous hospitalization within the past 6 months

Underlying metabolic disorder not related to anorexia nervosa (including chronic kidney disease, renal tubular disorders, and underlying endocrine disorders)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

10 Participants
are grouped into 2 trial groups