SEDentary Lifestyle, Mortality and Major Adverse Clinical Outcomes in Chronic KIDney Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40+
SponsorTurku University Hospital

About this trial

The goal of this study is to learn if a simple home exercise program can benefit patients with advanced chronic kidney disease. There is also an observational part of the study without an exercise program.

The study will record patients' mortality, cardiovascular events, emergency department visits, hospital stays, need for dialysis and 6 minutes walking distance. Also maximal oxygen uptake, quality of life and bone fractures are recorded and blood tests and X-rays analyzed. The prospective observational part of the study will investigate the link between cardiovascular and kidney health as well as exercise capacity and adverse outcomes.

Eligibility criteria

Qualifiers

Age >40 years

Estimated glomerular filtration rate < 20ml/min/1.73m2 (CKD stage 4-5)

Informed consent from the patient is received

Disqualifiers

Maintenance dialysis dependency before inclusion

Pregnant women

Patient's lack of commitment to follow-up

Chronic or acute clinical condition with a prognosis less than 6 months

Trial design

Treatments tested in this trial

  • EXERCISE TRAINING WITH OR WITHOUT MEDICATION

Treatment groups

400 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Turku University Hospital

Lead sponsor

Satasairaala

Collaborator

Vaasa Central Hospital, Vaasa, Finland

Collaborator