Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
ConditionLung Adenocarcinoma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-79
SponsorShanghai Pulmonary Hospital, Shanghai, China
About this trial
This study aims to evaluate the non-inferiority in recurrence-free survival and overall survival of segmentectomy compared with lobectomy in patients with lung adenocarcinoma ≤ 2 cm with micropapillary and solid subtype negative by intraoperative frozen sections.
Eligibility criteria
Qualifiers
Patient aged 20-79 years old, both male or female;
Tumor size <= 2cm on preoperative CT scan;
Peripheral solitary nodule or the associated lesion is MIA or less invasive lesion;
Preoperative CT indicated that the nodules were non-pure glass nodules (consolidation to tumor ratio >= 0.25);
Disqualifiers
Radiological pure ground glass nodules (consolidation to tumor ratio < 0.25);
The nodule is close to the lung hilus and is unable to perform segmentectomy;
Intraoperative frozen section confirmed with micropapillary and solid subtype positive (> 5%);
Intraoperative frozen section confirmed adenocarcinoma in situ and minimally invasive adenocarcinoma;
Trial design
Treatments tested in this trial
- Segmentectomy
- Lobectomy
Treatment groups
690 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov