About this trial
Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress. These problems that are hard to treat because access to mental health care is often limited. To help address this, the researchers created Lift, a fully automated mindfulness program designed with patient input and delivered through a mobile app. The investigators now plan a large, multi-site study to test whether Lift improves mental health and quality of life over six months compared to a critical illness education program called Enlighten Recovery. Overall the goal is to make an easy-to-use, widely accessible program available to people across the U.S., including those who speak Spanish.
Eligibility criteria
Qualifiers
Adult (age ≥18)
Managed in an ICU for ≥24 hours during the time inclusion criterion #3 is met
mechanical ventilation via endotracheal tube for ≥4 hours
non-invasive ventilation (CPAP, BiPAP) for ≥4 hours in a 24-hour period provided for acute respiratory failure
Disqualifiers
Severe psychological distress as assessed by endorsement of active suicidality (see Protection of Human Subjects document for study team management of this finding)
Failure to randomize within 1 month after discharge from the hospital to home
Failure to login to study app and access content within 2 weeks after randomization
Trial design
Treatments tested in this trial
- Lift mobile mindfulness
- Enlighten Recovery education program
Treatment groups
Sponsors and collaborators
Duke University
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Center for Complementary and Integrative Health (NCCIH)
Collaborator