Sensory and Cognitive Predictions, and Their Disruptions in Schizophrenia

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorCentre Psychothérapique de Nancy

About this trial

Disturbances in the sense of self and time could play an important role in the development of psychotic symptoms. Previous work has shown that patients have difficulty preparing to process information on the scale of a second, but are abnormally disturbed by slightly asynchronous information on the millisecond scale. In both cases, the anomalies could explain the patients' unusual experience of time. The hypothesis in neurotypical patients is that small delays or asynchronies asynchronies are treated as irrelevant information and ignored and ignored, whereas in patients suffering from schizophrenia they would disrupt the flow of time. This hypothesis is tested with a new visual illusion.

Eligibility criteria

Qualifiers

Male or female;

Age between 18 and 60 inclusive;

Subject having dated and signed the consent form prior to the start of any trial-related procedure (guardian or curator where applicable);

Member of a social security scheme or beneficiary of such a scheme.

Disqualifiers

Psychoactive substance use disorders (as defined by the DSM-V) (Diagnostic and Statistical Manual-V);

Use of benzodiazepines, hallucinogens (in the period preceding before inclusion, for a duration equivalent to 5 half-lives of the product) or cannabis (in the 2 months preceding inclusion);

Neurological pathology or sequelae;

Attention deficit hyperactivity disorder (ADHD);

Trial design

Treatments tested in this trial

  • Illusion task

Treatment groups

68 Participants
are divided into 1 treatment group

Sponsors and collaborators

Centre Psychothérapique de Nancy

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Collaborator