This study is a cross-over RCT evaluating the effectiveness of 3 sessions a week apart of explicit sensory retraining to the lower extremities in individuals with CIPN versus usual care. The primary outcome measures are TNAS for subjective symptoms, VAS for pain and TUG for mobility. Additional outcome measures are FABS for balance, sensory assessments - monofilaments for touch threshold, LEPT for proprioception, a home exercise log and a satisfaction questionnaire.
CIPN by self-report (present or absent) > 3 months after last chemotherapy treatment
age > 18.
Pre-chemotherapy neuropathy/ sensory impairment
recurrent falls prior to chemotherapy (more than 2 per year)
CNS involvement
not ambulatory before chemotherapy
Assaf-Harofeh Medical Center
Lead sponsor
Zefat Academic College
Collaborator