Sentinel Node Mapping in High Risk Endometrial Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-75
SponsorAC Camargo Cancer Center
About this trial
This study will evaluate the role of systematic lymphadenectomy after sentinel node (SLN) mapping in high risk endometrial cancer (high grade histologies or deep myometrial invasion). The participants will be randomized in a non-inferiority controlled trial in 2 groups: SLN mapping or SLN mapping followed by systematic lymphadenectomy.
Eligibility criteria
Qualifiers
High grade histologies (endometrioid grade 3, serous, clear cell and carcinosarcoma)
Endometrioid grades 1 or 2 with myometrial invasion of ≥50%
Endometrioid grades 1 or 2 with cervical invasion
Clinically suitable to receive systematic lymphadenectomy
Disqualifiers
Previous hysterectomy in other institution
Presence of extra-uterine disease (peritoneal, visceral or suspicious lymph node metastasis)
Previous pelvic node dissection
Trial design
Treatments tested in this trial
- Sentinel Node Mapping
- Lymphadenectomy
Treatment groups
178 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov