Septum-guided Segmentectomy for Deep Early-stage Lung Cancer (SGS2512)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorShanghai Chest Hospital

About this trial

The purpose of this study is to evaluate the safety and effectiveness of a specialized surgical technique called "Septum-guided Segmentectomy" for treating early-stage lung cancer located deep within the lung tissue.Standard surgery for lung cancer often involves removing an entire lung lobe (lobectomy), which can significantly reduce a patient's breathing capacity. For small tumors, removing only a segment of the lung (segmentectomy) can preserve more healthy tissue. However, for tumors located deep in the lung, traditional segmentectomy is technically challenging and risks leaving cancer cells behind.In this study, surgeons will use the natural anatomical boundaries-the intersegmental veins and their surrounding thin membranes (septa)-as a guide to precisely remove the target lung segment. This "septum-guided" approach aims to ensure the cancer is completely removed while maximizing the preservation of healthy lung function.Participants will be followed for 3 years after surgery to monitor for cancer recurrence and assess their long-term recovery.

Eligibility criteria

Qualifiers

Age 18-80 years

Clinical stage IA (cT1a-bN0M0)

tumor diameter ≤ 2 cm

Pathological feature: Solid-dominant lesion (CTR > 0.5)

Disqualifiers

Multiple pulmonary nodules or evidence of distant metastasis

Intraoperative confirmation of lymph node metastasis (N1/N2) or pleural dissemination

History of previous ipsilateral lung surgery

History of other malignant tumors within the past 5 years

Trial design

Treatments tested in this trial

  • Septum-guided Segmentectomy

Treatment groups

89 Participants
are divided into 1 treatment group

Sponsors and collaborators