Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorZhang longjiang,MD

About this trial

The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.

Eligibility criteria

Qualifiers

Age between 18 and 80 years old;

Known patients with non-obstructive coronary artery disease (disease duration ≥2 years);

Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations.

Disqualifiers

Patients who have experienced ACS or PCI/CABG;

Patients who have experienced adverse cardiovascular and cerebrovascular events;

Patients who have undergone follow-up CCTA or DSA examinations before enrollment;

Patients with severe hepatic and renal dysfunction;

Trial design

Treatments tested in this trial

  • Coronary Computed Tomography Angiography
  • Current clinical guidelines

Treatment groups

3,100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Zhang longjiang,MD

Lead sponsor

Jinling Hospital, China

Sponsor institution