Serum Bicarbonate Changes During Laparoscopic Bariatric Surgery
ConditionAcid Base Disorder
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIstinye University
About this trial
Pneumoperitoneum during laparoscopic bariatric surgery induces carbon dioxide absorption and may lead to perioperative alterations in acid-base balance. Serum bicarbonate (HCO₃-) plays a central role in metabolic compensation; however, the clinical relevance of perioperative bicarbonate changes remains insufficiently defined.
This prospective observational study aims to evaluate the association between pneumoperitoneum duration and perioperative serum bicarbonate change (ΔHCO₃-), and to investigate whether ΔHCO₃- is associated with early discharge readiness at 48 hours (DR-48) following laparoscopic bariatric surgery. Patients undergoing laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass will be enrolled consecutively. No alteration of routine clinical care will occur.
Eligibility criteria
Qualifiers
Adults aged ≥18 years
ASA physical status I-III
Scheduled for elective laparoscopic bariatric surgery (laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass)
Provided written informed consent
Disqualifiers
Age <18 years
ASA physical status IV or higher
Chronic obstructive pulmonary disease (COPD), asthma, or other severe chronic respiratory disease
Known chronic metabolic acidosis or renal failure
Trial design
Treatments tested in this trial
- Laparoscopic Bariatric Surgery
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov