Sevoflurane General Anesthetic and Spatial Memory in Humans
ConditionSpatial Memory Disorder
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30-50
SponsorUniversity of Chile
About this trial
The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is:
• A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines.
Participants will perform a virtual maze test and plasma samples will be taken before and after surgery.
Eligibility criteria
Qualifiers
Candidate for elective laparoscopic surgery of cholecystectomy.
Age 30 to 50 years.
Disqualifiers
Visual or hearing difficulties.
Malignant hyperthermia.
Being treated with centrally acting drugs, such as anxiolytics, antidepressants, antipsychotics, anticonvulsants, anticholinergics, and first-generation antihistamines.
Present a disorder of the sphere of neuropsychiatry
Trial design
Treatments tested in this trial
- Surgery/general anesthesia
Treatment groups
22 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov