Sex Differences in Exercise-Induced Hypoalgesia
ConditionHealthy Adult
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorCentro Universitario La Salle
About this trial
Exercise-induced hypoalgesia (EIH) refers to the reduction in pain sensitivity following acute exercise. Although aerobic exercise has been shown to induce hypoalgesia in healthy individuals, it remains unclear whether the magnitude of this response differs between men and women.
This quasi-experimental study aims to evaluate sex differences in pressure pain thresholds following a standardized aerobic exercise protocol using a lower-limb cycle ergometer. Pressure pain thresholds will be assessed before exercise, immediately after exercise, and 30 minutes after exercise in healthy adults aged 18 to 65 years.
The findings of this study may contribute to improving individualized exercise prescription strategies based on sex differences in pain modulation.
Eligibility criteria
Qualifiers
Healthy male and female adults
Age between 18 and 65 years
Able to perform moderate-to-vigorous aerobic exercise
Able to understand study procedures
Disqualifiers
Cardiovascular, respiratory, neurological, or metabolic diseases contraindicating exercise
Current musculoskeletal pain or injury
Analgesic medication use within 24 hours prior to testing
Vigorous exercise within 24 hours prior to testing
Trial design
Treatments tested in this trial
- Aerobic exercise using cycle ergometer
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Centro Universitario La Salle
Lead sponsor
Universidad Rey Juan Carlos
Collaborator
Source ClinicalTrials.gov