Shanghai Clinical Cohort - Adrenal Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorShanghai Jiao Tong University School of Medicine

About this trial

As a vital organ responsible for producing life-sustaining hormones, the adrenal gland is associated with a wide range of diseases. These diseases affect multiple systems throughout the body and carry a high rate of mortality and disability. Current diagnosis and treatment face several challenges: significant variability in hormone testing results, inaccurate localization via imaging techniques, unclear molecular characteristics of adrenal tumors, and difficulty in determining prognosis through pathology. Therefore, establishing a clinical research cohort for adrenal diseases is essential. Such a cohort will enable in-depth exploration of disease mechanisms, identification of disease subtypes, optimization of diagnostic criteria, evaluation of treatment efficacy, advancement of personalized medicine, and formulation of prevention and treatment strategies.

Eligibility criteria

Qualifiers

A signed and dated informed consent form

Commitment to abide by the study procedures and cooperate with the implementation of the entire study process

Patients diagnosed with adrenal diseases, including aldosteronism, Cushing's syndrome, pheochromocytoma, adrenocortical carcinoma, and congenital adrenal hyperplasia; regardless of whether they have received adrenal surgery, radiotherapy, and/or medication therapy

Aged between 18 and 75 years

Disqualifiers

Refuse to sign the informed consent form

Patients without adrenal diseases

Have specified diseases or conditions (physical or psychological, identified through physical examination) that warrant exclusion from the study

Trial design

Treatments tested in this trial

  • Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.

Treatment groups

600 Participants
are divided into 1 treatment group

Sponsors and collaborators

Shanghai Jiao Tong University School of Medicine

Lead sponsor

Ruijin Hospital

Sponsor institution

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Collaborator

RenJi Hospital

Collaborator

Shanghai Zhongshan Hospital

Collaborator

Shanghai Public Health Clinical Center

Collaborator