Shear Wave Elastography for Evaluation of Hydronephrosis in Pregnancy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorBeni-Suef University

About this trial

Hydronephrosis is common during pregnancy and is often physiological; however, it may also result from true obstruction requiring intervention. Differentiating between physiological and obstructive hydronephrosis remains a clinical challenge using conventional ultrasound.

This prospective observational study aims to evaluate the diagnostic accuracy of renal cortical stiffness measured by shear wave elastography (SWE) in differentiating obstructive from physiological hydronephrosis in pregnant women. Participants presenting with hydronephrosis will undergo clinical assessment, laboratory investigations, and ultrasound evaluation including SWE measurements.

The diagnostic performance of SWE will be assessed using receiver operating characteristic (ROC) analysis, and optimal cut-off values will be determined. The study aims to provide a safe, non-invasive, and quantitative tool to improve diagnosis and guide management in pregnant patients with hydronephrosis.

Eligibility criteria

Qualifiers

Pregnant women ≥12 weeks gestation with Loin Pain.

Sonographic evidence of hydronephrosis.

Age ≥18 years.

Provided informed consent

Disqualifiers

Chronic kidney disease (CKD).

Congenital renal anomalies.

Pre-eclampsia

Poor acoustic window.

Trial design

Treatments tested in this trial

  • Shear Wave Elastography (SWE)

Treatment groups

250 Participants
are divided into 1 treatment group

Sponsors and collaborators