About this trial
Diaphragmatic paralysis may lead to severe symptoms such as breathlessness and reduced physical capacity.
Diaphragmatic plication using Robotic-Assisted Thoracic Surgery (RATS) is a minimally invasive surgical technique developed to improve lung function by correcting diaphragmatic elevation.
While its benefits have been reported in retrospective reports, prospective studies are lacking.
This prospective observational cohort study aimsto evaluate the short- and long-term effects of robot-assisted diaphragmatic plication on subjective breathlessness, physical performance, lung function, blood gases, and imaging findings at five Swedish university hospitals: Gothenburg, Linköping, Lund, Umeå, and Uppsala.
Patients will be assessed preoperatively and postoperatively after one to three months and after one and three years.
Eligibility criteria
Qualifiers
Patients with symptomatic unilateral diaphragmatic paralysis persisting for ≥1 year
Patients are scheduled for RATS at thoracic surgery clinics in five Swedish university hospitals (Gothenburg, Linköping, Lund, Umeå, and Uppsala).
Disqualifiers
Inability to complete forms in Swedish
Neuromuscular disease as the cause of diaphragmatic paralysis
Other significant causes of dyspnea
Impaired physical capacity from other causes than diaphragmatic paralysis.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Uppsala County Council, Sweden
Lead sponsor
Uppsala University
Collaborator