SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65-100
SponsorPoznan University of Medical Sciences

About this trial

This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.

Eligibility criteria

Qualifiers

Patients with ASA classification I-III

Aged 65-100 years

Who will be scheduled for hip arthroplasty under spinal anesthesia

Disqualifiers

Patients who have a history of bleeding diathesis

Take anticoagulant therapy

History of chronic pain before surgery

Multiple trauma

Trial design

Treatments tested in this trial

  • sodium Chloride
  • Ropivacaine Hydrocloride

Treatment groups

60 Participants
are divided into 2 treatment groups