Research is to compare and evaluate the clinical and radiographic outcomes of the enamel matrix derivative with or without connective tissue wall graft for noncontained infrabony defects using simplified papilla preservation technique .
Patients willing to participate in the study.
Participants aged ≥18 years to 55 years.
Presented with non contained infra bony defects.
Presence of at least 1 non contained infra bony defect(IBD) with a pocket probing depth ≥6mm after reevaluation of the hygienic phase and a depth of IBD ≥3mm as detected on radiographs, with radiographic angulation of ≥37⸰ , and exhibiting a 1 or 2 wall infra bony defect15(assessed by a bone sounding and confirmed intrasurgically)
Grade III mobility, endodontically treated teeth.
Pregnant and lactating females.
History of tobacco smoking .
Patients with systemic disease.