Singapore Perioperative Ageing Study (Sing-PAS)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65-100
SponsorNational University Hospital, Singapore
About this trial
The specific aim of the study will be to set up a perioperative database to longitudinally track the progress of elderly patients undergoing major surgery from the preoperative period to five years postoperatively. This database will form the foundation of a programme that will be sustainable through future grants to implement clinical strategies to improve outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Elderly patients aged 65 years and above
Undergoing major non-cardiac surgery, defined as surgery that is predicted to be at least 2 hours and requiring at least 1 day postoperative stay in the hospital
English, Chinese or Malay speaking
Ability to provide informed consent
Disqualifiers
History of psychiatric disease
Illiterate
An active history of substance abuse.
Undergoing neurological procedures
Trial population
Elderly patients aged 65 and above who are planned for major non-cardiac surgery predicted to be at least 2 hours in duration and requiring at least 1 postoperative stay in hospital.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Neurocognitive tests and blood taking
Other interventionBattery of neurocognitive tests and questionnaires including MoCA, PHQ-9, Falls History, FIFE, STOPBANG, Nutritional Survey, Global Physical Activity Questionnaire, Brief Pain Index, Brief Psychiatric Rating Scale, NuDESC, 3D-CAM. Blood taking.
Treatment groups
600 Participants
are divided into 1 treatment groupGroup A: Surgical Cohort1 intervention
Trial outcomes
Primary outcomes
1
Development of POD in elderly patients undergoing major non-cardiac surgery in a tertiary hospital in Singapore
Collection of patient's demographics, medical records and surgical records to establish risk factors for POD development
Time frame
Before surgery through to 5 years post surgerySponsors and contacts
Click on the lead sponsor to view all of their trials.
National University Hospital, Singapore
Lead sponsor
National University of Singapore
Collaborator
Source ClinicalTrials.gov