Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS)
ConditionBreast Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age50+
SponsorMaisonneuve-Rosemont Hospital
About this trial
Eligible women will receive neoadjuvant single fraction radiotherapy followed by surgery performed after one year
Eligibility criteria
Qualifiers
Female aged 50 years or older.
Postmenopausal status (Defined as: age 60 OR bilateral ovariectomy OR amenorrhea > 12 months prior to breast cancer diagnosis without using oral contraceptives/hormone replacement therapy) (65).
World Health Organization (WHO) performance status 0-2.
Invasive ductal carcinoma proven by biopsy done ≤ 12 weeks from treatment start.
Disqualifiers
Age less than 50 years.
Premenopausal or uncertain menopausal status.
A known deleterious mutation in BRCA 1 and/or BRCA 2.
Clinical tumor size > 2.0 cm in greatest diameter on staging ultrasound.
Trial design
Treatments tested in this trial
- Radiation: Single Pre-Operative Radiation Therapy
Treatment groups
80 Participants
are divided into 1 treatment groupSponsors and collaborators
Maisonneuve-Rosemont Hospital
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborator
Source ClinicalTrials.gov