Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorVastra Gotaland Region

About this trial

Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP). In current clinical practice, both single-session and multiple-session PRP approaches are widely accepted and utilized. The purpose of this study is to compare the safety and effectiveness of single-session and multiple-session PRP.

Eligibility criteria

Qualifiers

Age > 18 years.

Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.

Visual acuity ≥ 0.1 Snellen.

CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.

Disqualifiers

Intraocular surgery within the last 4 months or planned within the next 3 months.

Previous or current center-involved diabetic macular edema (Ci-DME).

Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.

Treatment with medications known to risk macular edema.

Trial design

Treatments tested in this trial

  • Single-session panretinal PRP (SS-PRP)
  • Multiple-session panretinal PRP (MS-PRP)

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators