About this trial
Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP). In current clinical practice, both single-session and multiple-session PRP approaches are widely accepted and utilized. The purpose of this study is to compare the safety and effectiveness of single-session and multiple-session PRP.
Eligibility criteria
Qualifiers
Age > 18 years.
Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.
Visual acuity ≥ 0.1 Snellen.
CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.
Disqualifiers
Intraocular surgery within the last 4 months or planned within the next 3 months.
Previous or current center-involved diabetic macular edema (Ci-DME).
Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.
Treatment with medications known to risk macular edema.
Trial design
Treatments tested in this trial
- Single-session panretinal PRP (SS-PRP)
- Multiple-session panretinal PRP (MS-PRP)