About this trial
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.
Eligibility criteria
Qualifiers
Age 18-80 years
ASA (American Society of Anesthesiologists) II-IV
Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)
Disqualifiers
Emergency surgery
Presence of perioperative arrhythmia
<35% left ventricular ejection fraction
>50 mmHg systolic pulmonary artery pressure
Trial design
Treatments tested in this trial
- Single Step Lung Recruitment Maneuver
- Stepwise Lung Recruitment Maneuver