SIRT Versus cTACE for Unresectable HCC (CHANCE2506)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorZhongda Hospital

About this trial

To evaluate the efficacy and safety of yttrium-90 carbon microspheres versus cTACE in patients with unresectable hepatocellular carcinoma

Eligibility criteria

Qualifiers

Eastern Cooperative Oncology Group performance status ≤ 1;

Expected survival time ≥ 3 months;

Confirmed hepatocellular carcinoma based on CNLC guidelines;

Without extrahepatic metastases, unresectable or refuse surgical resection;

Disqualifiers

With previous history of hepatic encephalopathy;

Extrahepatic disease or combined with other malignant tumors;

Infiltrative hepatocellular carcinoma ;

With prior antitumor therapies, including liver transplantation, hepatectomy, ablation, TACE, chemotherapy, radiotherapy, targeted therapy or immunotherapy;

Trial design

Treatments tested in this trial

  • SIRT
  • cTACE

Treatment groups

108 Participants
are divided into 2 treatment groups

Sponsors and collaborators