Sitting Interruption and Whole-body Cardiovascular Health
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-60
SponsorUniversity of North Carolina, Chapel Hill
About this trial
There is strong evidence for the association between sedentary behaviors and cardiovascular diseases such as coronary heart disease and stroke. However, the public currently has no clear guidance on how to limit or interrupt their sedentary behaviors. This study will identify and test the physiological effects of several sedentary behavior interruption strategies and explore the feasibility (i.e., likelihood of an individual performing the requested activities) of those strategies to inform the development of public policy surrounding sedentary behavior interruption. Long-term, the findings of this study will inform a large clinical trial that can test whether sedentary behavior reduction can decrease cardiovascular disease risk.
Eligibility criteria
Qualifiers
Aged between 30-60 years
Insufficiently active: self-reported exercise <90 minutes per week for the past 3 months
Sedentary: self-reported sitting >8 hours per day
Self-reported ability to walk 4 blocks and climb 2 flights of stairs
Disqualifiers
Use of assisted-walking devices
Comorbid condition that would limit the ability to reduce sedentary behavior (e.g., musculoskeletal condition, current chemotherapy)
Plans for major surgery within next 3 months
Recent history (<1 year) of ischemic heart disease, chronic heart failure, stroke, or chronic kidney disease
Trial design
Treatments tested in this trial
- One 5-Minute Walking Bout Each Hour
- One 15-Minute Standing Bout Each Hour
- One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour
- Uninterrupted Sitting
Treatment groups
56 Participants
are divided into 4 treatment groupsSponsors and collaborators
University of North Carolina, Chapel Hill
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov