Skeletal Muscle Energetics and Fatiguability in Older Individuals
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age60-90
SponsorJohns Hopkins University
About this trial
The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.
Eligibility criteria
Qualifiers
Participants who are >= 60 years of age
HIV serostatus positive participants on stable antiretroviral therapy (ART) (no regimen change in last month) with undetectable HIV viral load (<100 copies).
HIV serostatus negative participants
Disqualifiers
Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent
Contraindications to MRI
Significant cardiovascular, pulmonary or musculoskeletal or orthopedic disease that significantly limits exercise capacity
Significant lower extremity peripheral vascular disease.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
200 Participants
are grouped into 2 trial groupsSponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov