Skin Barrier Function in Women Using UV Nail Lamps
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-50
SponsorUniversity of Split, School of Medicine
About this trial
The goal of this observational study is to compare objective parameters of skin barrier function between healthy adult women who regularly use UV lamps during nail treatments and women who do not use UV lamps.
The main questions it aims to answer are:
* Do women who regularly use UV lamps for nail treatments show differences in skin barrier function compared to women who do not use UV lamps? * Are transepidermal water loss, skin hydration, and erythema associated with regular exposure to UV lamps used for nail treatments? * Does the duration of UV lamp use influence skin barrier function parameters?
Researchers will compare women who regularly use UV lamps during nail treatments with women who have natural nails and do not regularly expose their hands to UV lamps.
Participants will:
* Attend a single study visit. * Complete a short questionnaire regarding nail care habits and duration of UV lamp use. * Undergo non-invasive measurements of skin barrier function on the hands, including transepidermal water loss, skin hydration, and erythema assessments.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Healthy adult women (≥18 years of age)
Willing and able to provide written informed consent
Willing to complete the study questionnaire
Disqualifiers
Active skin diseases (e.g., psoriasis, vitiligo, or other dermatological conditions)
Allergic contact dermatitis
Pregnancy or breastfeeding
Use of topical or systemic corticosteroids, immunosuppressive drugs, or antihistamines
Trial population
Healthy adult women recruited from the general population. Participants will be classified into two groups based on their self-reported use of UV nail lamps during nail treatments: regular users of UV nail lamps and women who do not regularly use UV nail lamps and have natural nails.
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
30 Participants
are grouped into 2 trial groupsGroup A: Regular UV Nail Lamp Users
Group B: Non-Users of UV Nail Lamps
Trial outcomes
Primary outcomes
1
Change in Transepidermal Water Loss (TEWL)
Skin barrier function will be assessed by measuring transepidermal water loss using a Tewameter TM 300 probe. Values will be expressed in g/m²/h
Time frame
Single assessment during the study visit2
Change in Skin Hydration
Hydration of the stratum corneum will be assessed using a Corneometer CM 825 probe.
Time frame
Single assessment during the study visit3
Change in Skin Erythema
Skin erythema will be assessed using a Mexameter MX 18 probe.
Time frame
Single assessment during the study visitSponsors and contacts
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Source ClinicalTrials.gov